Diagnostic solutions for multiple industries

We are the inventors of Veriflow® technology, a patented, DNA Signature Capturing Technology that draws from our core competencies in molecular diagnostics, antibody design, and immunoassays. Our Veriflow® test kits are finding applications across multiple industries. We help the food industry to detect foodborne pathogens. We work with winemakers and beer artisans to cost-effectively improve the quality of their products. And we can apply Veriflow® technology to challenges in other industries, too, designing custom solutions for healthcare, veterinary services, biodefense, and environmental testing. Each solution is specific, but each retains the inherent advantages of Veriflow® technology—it’s simple, accessible, and affordable.

Milestones on the road to new diagnostics

As a global molecular solutions company, Invisible Sentinel is providing multiple industries with the advantages of Veriflow® test kits for wide-ranging diagnostic uses. Here are some of the highlights of our journey.

  • October 2006
  • August 2009
  • September 2009
  • September 2011
  • October 2011
  • January 2012
  • March 2012
  • May 2012
  • June 2012
  • October 2012
  • June 2013
  • July 2013
  • December 2013
  • December 2013
  • January 2014
  • March 2014
  • August 2014
  • September 2014
  • September 2015
  • December 2015

October 2006

Invisible Sentinel founded by Nick Siciliano and Ben Pascal, entrepreneurs with backgrounds in R&D and product development; R&D labs established at the University City Science Center in Philadelphia.

August 2009

Prototype of pathogen-detection technology demonstrated to minimize sample preparation and reduce time to results.

September 2009

R&D facilities expanded and fitted out for cell-culture laboratories.

September 2011

Initial patent awarded to Invisible Sentinel by US Patent and Trademark Office for a diagnostic system to identify contaminants from an environmental sample.

October 2011

Invisible Sentinel named “2011 Best Early Stage Company” in the Philadelphia region by the Philadelphia Business Journal and Pennsylvania BIO.

January 2012

Custom Diagnostic Solutions Program launched.

March 2012

First design of Veriflow® technology validated.

May 2012

Second patent issued, providing further protection for a diagnostic device to identify pathogenic bacteria in food and beverages.

June 2012

Manufacturing facility expanded for launch of food diagnostics.

October 2012

Veriflow® Campylobacter Assay (Veriflow® CA), the initial Veriflow® food diagnostic, certified by the Association of Analytical Communities (AOAC) to detect Campylobacter jejuni and Campylobacter coli in poultry.

Invisible Sentinel named “2012 Best Mid-Stage Company” in the Philadelphia region by the Philadelphia Business Journal and Pennsylvania BIO.

June 2013

Veriflow® Listeria monocytogenes (Veriflow® LM) awarded AOAC Certification to detect Listeria monocytogenes in foods.

July 2013

Next-generation Veriflow® cassette introduced to the marketplace.

Third patent for Veriflow® technology issued, providing additional claims.

December 2013

Partnership formed with Jackson Family Wines to develop a same-day test for wine-spoilage organisms.

December 2013

New Company headquarters fit-out begins and manufacturing facilities triple in size.

January 2014

Veriflow® Listeria species (Veriflow® LS) awarded AOAC Certification to detect Listeria species in foods.

March 2014

Veriflow® Brettanomyces bruxellensis (Veriflow® BRETT) marketed by Invisible Sentinel and Jackson Family Wines to detect Brettanomyces bruxellensis, a yeast that can affect the taste and aroma of wine.

Veriflow® Salmonella species (Veriflow® SS) awarded AOAC Certification to detect Salmonella species in foods.

August 2014

Invisible Sentinel takes ownership over its new corporate headquarters expanding production and R&D facilities and capabilities.

September 2014

Partnership formed with Victory Brewing Company to develop a same day test for beer spoilage organisms.

September 2015

Partnership announced with Refresco Gerber, Europe’s largest juice bottler, to develop same day test for juice spoilage organisms.

December 2015

As a Global Molecular Solutions Company, Veriflow technology is actively sold in 18 countries.

Company Vision

At Invisible Sentinel, we develop first in class, next generation technologies for microbial detection. As innovators in rapid diagnostics, we focus on developing leading edge molecular detection solutions that quickly provide highly accurate information on the presence of harmful microbes.

Uniquely designed for easy, practical use on-site and throughout the entire supply chain— our patented and regulatory approved Veriflow® Technology promises to create a new standard for rigorous quality control.

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Management Team

  • Nicholas Siciliano

    Chief Executive Officer and co-founder

     

    Nicholas Siciliano

    Chief Executive Officer and co-founder

    Dr. Siciliano co-founded Invisible Sentinel in 2006 and was the lead inventor of the Company’s Veriflow technology. In his role as CEO, he sets corporate strategy, including sales & marketing initiatives and the identification of strategic partnerships. He also continues to lead the R&D team, drawing on his more than 15 years of experience in microbiology, immunology, and assay development.

    • Earned a B.S. in Chemistry from Villanova University and a Ph.D. in Immunology & Microbial Pathogenesis from Thomas Jefferson University
    • Former biomedical researcher in bacterial & viral pathogenesis, immunology, microbiology, and oncology.
    • Developer of antibody-based assays and consultant on projects in bacteriology, immunology, and antibody design.
    • Honoree on the annual “40 under 40” list compiled by the Philadelphia Business Journal to recognize outstanding entrepreneurs and business leaders.
    • 2015 Marcum/Smart CEO Innovator of the Year
  • Benjamin Pascal

    Chief Business Officer and co-founder

     

    Benjamin Pascal

    Chief Business Officer and co-founder

    Mr. Pascal co-founded Invisible Sentinel in 2006. In his role as Chief Business Officer, he focuses on marketing and business development. He also works closely with the Sales function of the company, helping to define sales strategies, identifying potential clients, and opening new international markets for the Company.

    • Former product developer at B. Braun Medical and the National Institute for Medical Research (London).
    • An inventor on a corresponding patent to an antibacterial device and team member in the design of a functional cellular vaccine against malaria.
    • Graduate of The George Washington University in Biology and Political Science and of Lehigh University with an MBA.
    • Honoree on the annual “40 under 40” list compiled by the Philadelphia Business Journal to recognize outstanding entrepreneurs and business leaders.
  • Paul Touhey

    Executive Chairman

     

    Paul Touhey

    Executive Chairman

    Mr. Touhey works closely with the executive management of Invisible Sentinel to guide the strategic direction of the company. He brings to Invisible Sentinel more than 25 years of executive experience in the life-sciences and diagnostics industries and a record of fostering corporate success throughout his career. As the Chief Executive Officer of Fujirebio Diagnostics, he led that company to become an industry leader in cancer diagnostics.

    • Former CEO of Fujirebio Diagnostics and member of the Board of Directors of Fujirebio Diagnostics and its corporate parent, Fujirebio Inc.
    • Former Vice President of Operations in the Diagnostics Division of Centocor, Inc.
    • Member of the Board of Directors of the University City Science Center and, previously, of Orthovita, Inc., a biomaterials company, and Cernostics, Inc., a molecular-cancer-diagnostics company.
    • Recipient of both the Leadership Award and the CEO of the Year Award from Pennsylvania BIO.
  • Patrick Courtney

    Vice President, Operations

     

    Patrick Courtney

    Vice President, Operations

    Mr. Courtney directs the manufacture of the complete line of Veriflow test kits at Invisible Sentinel’s expanded production facility. He is responsible for the good manufacturing practice and efficient delivery required to ensure that every Invisible Sentinel customer will benefit from the inherent advantages of Veriflow® technology.

    • Former director of process-improvement and quality-assurance programs in various corporate settings, including Medco Health Solutions, Fresenius Medical Care, and Centocor, Inc., and a Six Sigma Master Black Belt.

Board of Directors

  • Paul Touhey

    Executive Chairman

     

    Paul Touhey

    Executive Chairman

    • Former Chief Executive Officer of Fujirebio Diagnostics with more than 25 years of senior-executive experience in the diagnostics and life-science industries, and former member of the Board of Directors of Fujirebio Diagnostics and its corporate parent, Fujirebio Inc.
    • Former Vice President of Operations in the Diagnostics Division of Centocor, Inc.
    • Member of the Board of Directors of the University City Science Center and, previously, of Orthovita, Inc., a biomaterials company, and Cernostics, Inc., a molecular-cancer-diagnostics company.
    • Recipient of both the Leadership Award and the CEO of the Year Award from Pennsylvania BIO.
  • Benjamin Pascal

    Chief Business Officer and co-founder

     

    Benjamin Pascal

    Chief Business Officer and co-founder

    • Co-founder of Invisible Sentinel and head of marketing and business development.
    • Former product developer at B. Braun Medical and the National Institute for Medical Research (London).

     

  • Nicholas Siciliano

    Chief Executive Officer and co-founder

     

    Nicholas Siciliano

    Chief Executive Officer and co-founder

    • Co-founder and head of corporate strategy, including R&D strategy and the identification of strategic partnerships.
    • Former biomedical researcher in the field of bacterial pathogenesis at the University of Pennsylvania Medical School.

     

  • Greg Betzler

    Board Member

     

    Greg Betzler

    Board Member

    • Former Chief Executive Officer and co-owner of Betzler Manufacturing, Inc., a precision manufacturer of surgical implants and instruments.
  • Bruce Peacock

    Board Member

     

    Bruce Peacock

    Board Member

    • Venture partner at SV Life Sciences Advisors, with more than 30 years of executive experience in the life-sciences industry.
    • Former Chief Financial and Business Officer of Opthotech, Inc., a developer of biopharmaceuticals for eye diseases.
    • Former Chief Operating Officer of Cephalon, Inc. with oversight of the successful launch of Provigil®, Cephalon’s first proprietary pharmaceutical product.
    • Former Chief Executive Officer of Orthovita Inc. and Adolor Corp.
    • Former Chief Financial Officer of Centocor, Inc., instrumental in raising over $850 million through debt and equity issues and corporate alliances.
  • John Blair

    Board Member

     

    John Blair

    Board Member

    • Former senior trader at Salomon Brothers and Credit Suisse, with more than 30 years experience in the financial services industry.

     

     

  • Brian McElwee

    Board Member

     

    Brian McElwee

    Board Member

    • President of Valley Forge Investment Corporation, a real-estate company.
  • Michael Young

    Board Member

     

    Michael Young

    Board Member

    • Founder of Classic Management Inc., one of the largest property-management companies in Philadelphia.
  • Roger Hochstin

    Board Member

     

    Roger Hochstin

    Board Member

    • Founding partner of Hochstin Jakobson and a member of the New York Stock Exchange.
    • Member of the Board of Directors of Glaceau until its acquisition by Coca Cola Co. for $4.1 billion.

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